Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075812 | 1.00 | ALOX5 (0.45) | ALOX5LMNAMAPTKMT2ACYP3A4 | |
| SCHEMBL9075806 | 1.00 | ALOX5 (0.45) | ALOX5LMNAMAPTKMT2ACYP3A4 | |
| SCHEMBL9074404 | 0.81 | ALOX5 (0.41) | ALOX5LMNAMAPTKMT2A | |
| SCHEMBL9074407 | 0.81 | ALOX5 (0.41) | ALOX5LMNAMAPTKMT2A | |
| SCHEMBL9074400 | 0.81 | ALOX5 (0.41) | ALOX5LMNAMAPTKMT2A | |
| SCHEMBL9075180 | 0.81 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9077212 | 0.80 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9077205 | 0.80 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9077210 | 0.80 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9075981 | 0.78 | ALOX5 (0.50) | ALOX5LMNAMAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |