Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074689 | 0.93 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL1119150 | 0.85 | JAK2 (0.57) | MEN1KMT2AKDM4EL3MBTL1SLC6A4 | |
| SCHEMBL7143354 | 0.84 | BCHE (0.47) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7148350 | 0.84 | PTGES (0.53) | — | |
| SCHEMBL9077723 | 0.82 | PTGDR2 (0.58) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7148366 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EPKML3MBTL1HTR2C | |
| SCHEMBL1300234 | 0.79 | HPGD (0.60) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL7143453 | 0.79 | PTGES (0.49) | — | |
| SCHEMBL8393097 | 0.79 | GAA (0.61) | MEN1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28847207 | 0.78 | KDM4E (0.54) | MEN1KMT2AALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |