Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011527 | 0.88 | ALDH1A1 (0.50) | ALDH1A1PARLSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL30890353 | 0.87 | ALDH1A1 (0.41) | TBXA2RALDH1A1PARLSMN1; SMN2KMT2A | |
| SCHEMBL12902109 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL15875070 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL21612886 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL23636470 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL3922312 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL13101828 | 0.86 | STAT3 (0.49) | TBXA2RALDH1A1FFAR4ENPP3ENPP1 | |
| SCHEMBL7957938 | 0.84 | STAT3 (0.50) | TBXA2RALDH1A1ENPP3ENPP1 | |
| SCHEMBL907441 | 0.83 | ALDH1A1 (0.43) | ALDH1A1PARLSMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | TP53, TP53BP1, SIRT1 | TBXA2R 4124/4885ALDH1A1 2250/4885ALOX15 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.