Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monomethyl Ester SCHEMBL9078007 | 0.91 | XDH (0.53) | XDHALDH1A1FBP1CA1CA2 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL9440650 | 0.91 | XDH (0.53) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL9339856 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL69167 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL2126364 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL9681086 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL9681088 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL69166 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL2615887 | 0.80 | ALDH1A1 (0.68) | XDHALDH1A1FBP1CA1CA2 | |
| SCHEMBL9078329 | 0.80 | TTR (0.58) | FBP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519953-A1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH. | UNIV TORONTO (CA) | 1992-12-30 | — | — | EP | claimed |
| WO-1991013891-A1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH | THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) | 1991-09-19 | — | — | WO | claimed |
| EP-0519953-B1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH | UNIV TORONTO (CA) | 1996-02-07 | — | — | EP | disclosed |
| US-5334707-A | Crosslinking | UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION, THE (CA) | 1994-08-02 | — | — | US | disclosed |
| EP-0519953-A1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH. | UNIV TORONTO (CA) | 1992-12-30 | — | — | EP | disclosed |