Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076525 | 1.00 | ALOX5 (0.34) | ALOX5ADORA3SLC6A3LOXLOXL2 | |
| SCHEMBL9077334 | 0.83 | — | — | |
| SCHEMBL9074240 | 0.82 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9076779 | 0.80 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9076775 | 0.80 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9049989 | 0.76 | — | — | |
| SCHEMBL9076629 | 0.76 | — | — | |
| SCHEMBL9049240 | 0.72 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9076169 | 0.72 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9050480 | 0.70 | ALOX5 (0.38) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |