Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.50 |
| ▸ | FAP | Q12884 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 9/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074959 | 0.87 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9076978 | 0.85 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9077055 | 0.84 | DPP4 (0.48) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9077159 | 0.84 | F2 (0.51) | F2PRSS1 | |
| SCHEMBL9073722 | 0.78 | F2 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9075894 | 0.76 | F2 (0.77) | F2 | |
| SCHEMBL9075695 | 0.75 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8191997 | 0.75 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL23256155 | 0.75 | F2 (0.53) | F2 | |
| SCHEMBL9076761 | 0.74 | F2 (0.78) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623596-A1 | N-acylpyrrolidines or N-acylpiperidines having a guanidinyl- or amidinyl-substituted side chain as thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |