Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.61 |
| ▸ | FAP | Q12884 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202019 | 0.85 | ALDH1A1 (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6164069 | 0.82 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL31412199 | 0.80 | OPRM1 (0.66) | OPRM1OPRD1 | |
| SCHEMBL30833622 | 0.80 | OPRM1 (0.66) | OPRM1OPRD1 | |
| SCHEMBL29702054 | 0.80 | OPRM1 (0.66) | OPRM1OPRD1 | |
| SCHEMBL9076481 | 0.80 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9076485 | 0.80 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9075661 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9414137 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9075665 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090786-A | HALOPYRROLE AMIDATED AMINO ACID USEFUL FOR INHIBITING SERINE PROTEASE ACTIVITY | FONDATECH BENELUX N.V. (BE) | 2000-07-18 | — | — | US | disclosed |