Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274866 | 0.82 | KCNH2 (0.41) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL9077025 | 0.81 | KCNH2 (0.50) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9078685 | 0.80 | KCNH2 (0.51) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL9077056 | 0.80 | KCNH2 (0.53) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL9274868 | 0.78 | GRIN1 (0.52) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL9089467 | 0.78 | KCNH2 (0.49) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL11836171 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11829251 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL9090055 | 0.75 | CYP2C19 (0.47) | HSD11B1ALDH1A1LMNAHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL11832279 | 0.75 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532629-B1 | 1-PIPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES | MERRELL PHARMA INC (US) | 1996-11-06 | — | — | EP | disclosed |