Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597046 | 0.82 | NLRP3 (0.50) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL6698144 | 0.81 | ALDH1A1 (0.38) | NLRP3ALDH1A1LMNATP53 | |
| SCHEMBL23343716 | 0.72 | NLRP3 (0.43) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL424522 | 0.69 | — | — | |
| SCHEMBL28096 | 0.69 | — | — | |
| SCHEMBL3913999 | 0.67 | ALDH1A1 (0.46) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL777321 | 0.67 | ALDH1A1 (0.52) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL597045 | 0.67 | NLRP3 (0.39) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL12854151 | 0.67 | NLRP3 (0.39) | NLRP3KDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL5784436 | 0.67 | CA1 (0.44) | NLRP3KDM4ECYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |