Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123756 | 0.82 | CA2 (0.34) | CA2SIGMAR1 | |
| SCHEMBL14307903 | 0.81 | CYP2C19 (0.41) | CA2SIGMAR1ALDH1A1 | |
| SCHEMBL3952930 | 0.81 | CYP2C19 (0.41) | CA2SIGMAR1ALDH1A1 | |
| SCHEMBL9209151 | 0.79 | CA2 (0.36) | CA2SIGMAR1 | |
| SCHEMBL28866445 | 0.78 | CA2 (0.33) | CA2 | |
| SCHEMBL27898374 | 0.78 | CPT2 (0.33) | CA2SIGMAR1 | |
| SCHEMBL14307904 | 0.74 | KCNH2 (0.38) | SIGMAR1ALDH1A1 | |
| SCHEMBL1067073 | 0.73 | MIF (0.34) | CA2SIGMAR1 | |
| SCHEMBL30423996 | 0.72 | CA2 (0.33) | CA2 | |
| SCHEMBL29975910 | 0.72 | CA2 (0.33) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510488-A | Process for trans-6- 2-(substituted-pyrrol-1-yl)alkyl!pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |