⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232533 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL23532612 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL377773 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL3974544 | 0.93 | — | — | |
| Tetrahydrofuran SCHEMBL11305285 | 0.77 | ALDH1A1 (0.36) | — | |
| Methacrylic Acid SCHEMBL203065 | 0.75 | TGFBR1 (0.31) | — | |
| SCHEMBL5941026 | 0.72 | TDP1 (0.48) | — | |
| SCHEMBL8108578 | 0.71 | — | — | |
| SCHEMBL621618 | 0.69 | — | — | |
| SCHEMBL1776275 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309142-B1 | METHOD FOR PREPARING CITALOPRAM DIOL INTERMEDIATE | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2020-08-05 | — | — | EP | claimed |
| US-10227293-B2 | Method for preparing citalopram diol intermediate | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD (CN) | 2019-03-12 | — | — | US | claimed |
| US-20180162805-A1 | METHOD FOR PREPARING CITALOPRAM DIOL INTERMEDIATE | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD (CN) | 2018-06-14 | — | — | US | claimed |
| EP-3309142-A1 | METHOD FOR PREPARING CITALOPRAM GLYCOL INTERMEDIATE | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2018-04-18 | — | — | EP | claimed |
| CN-107848958-A | A kind of preparation method of citalopram diol intermediate | 浙江华海药业股份有限公司 | 2018-03-27 | — | — | CN | claimed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | claimed |
| CN-101309924-A | Method for the preparation of escitalopram | LUNDBECK & CO AS H (DK) | 2008-11-19 | — | — | CN | claimed |
| EP-1951726-A2 | METHOD FOR THE PREPARATION OF ESCITALOPRAM | H.Lundbeck A/S (DK) | 2008-08-06 | — | — | EP | claimed |
| WO-2007054105-A2 | METHOD FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2007-05-18 | — | — | WO | claimed |
| US-6967259-B2 | Process for the preparation of Citalopram intermediate | PHARMACHEM TECHNOLOGIES LIMITED (GB) | 2005-11-22 | — | — | US | claimed |
| CN-1556800-A | Process for the preparation of citalopram | ҩ�ﻯѧ��������˾ | 2004-12-22 | — | — | CN | claimed |
| EP-1430044-A1 | PROCESS FOR THE PREPARATION OF CITALOPRAM | Pharmachem Technologies Limited (GB) | 2004-06-23 | — | — | EP | claimed |
| US-20030153774-A1 | Process for the preparation of citalopram | PHARMACHEM TECHNOLOGIES LIMITED, (GB) | 2003-08-14 | — | — | US | claimed |
| WO-2003029236-A1 | PROCESS FOR THE PREPARATION OF CITALOPRAM | PHARMACHEM TECHNOLOGIES LIMITED (GB) | 2003-04-10 | — | — | WO | claimed |
| US-20250073204-A1 | ANALOGS OF CYCLOBENZAPRINE AND AMITRYPTILENE | TONIX Pharmaceuticals Holding Corp (US) | 2025-03-06 | — | — | US | disclosed |
| US-12156864-B2 | Analogs of cyclobenzaprine and amitryptilene | TONIX Pharmaceuticals Holding Corp (US) | 2024-12-03 | — | — | US | disclosed |
| US-20230149348-A1 | ANALOGS OF CYCLOBENZAPRINE AND AMITRYPTILENE | TONIX Pharmaceuticals Holding Corp (US) | 2023-05-18 | — | — | US | disclosed |
| US-4113726-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-3984419-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3952017-A | 5-HYDROXY-5-(METHYL OR ALKYLMETHYL-AMINOPROPYL)- 5H-DIBENZO(A,D)CYCLOHEPTENES, ANTIDEPRESSANT | HOFFMANN-LA ROCHE INC. (US) | 1976-04-20 | — | — | US | disclosed |