SCHEMBL9077878

SCHEMBL9077878

Cc1ccc(C(=O)CCCC(C)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MEN1 O00255 2/20 0.47
GSK3B P49841 1/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 2/20 0.45
USP5 P45974 1/20 0.44
LTB4R Q15722 1/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CTNNB1 P35222 1/20 0.43
WNT3A P56704 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
HSD17B3 P37058 2/20 0.42
PDE4B Q07343 1/20 0.41
CYP1A2 P05177 1/20 0.41
HTR7 P34969 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15723441 0.81 L3MBTL1 (0.63) KMT2ANPC1RAB9ALMNAMAPT
SCHEMBL9410799 0.81 NPC1 (0.61) KMT2ANPC1RAB9AMEN1LMNA
SCHEMBL9665132 0.80 L3MBTL1 (0.67) KMT2ANPC1RAB9ALMNAMAPT
SCHEMBL9419411 0.80 KMT2A (0.69) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL8775647 0.79 ALDH1A1 (0.58) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL13686391 0.79 KMT2A (0.50) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL8402203 0.78 KMT2A (0.67) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL777295 0.78 KMT2A (0.49) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL2743310 0.77 KMT2A (0.78) KMT2ANPC1RAB9AMEN1GSK3B
SCHEMBL5849125 0.77 KMT2A (0.78) KMT2ANPC1RAB9AMEN1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5504244-A 3-(4-N-PENTYLPHENYLACYL)BENZOIC ACID OR SALT OR ESTER BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1996-04-02 US disclosed