Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374101 | 1.00 | PTGS1 (0.46) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL1512927 | 0.82 | OTC (0.42) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL1768730 | 0.82 | OTC (0.42) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL1768732 | 0.82 | OTC (0.42) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL7188599 | 0.82 | OTC (0.42) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL28634437 | 0.81 | PTGS1 (0.51) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL9372532 | 0.81 | PTGS1 (0.51) | PTGS1SLC7A11OTCGRIK1GRIK2 | |
| SCHEMBL13585138 | 0.79 | DNM1 (0.45) | OTCGRIK1GRIK2GRM1GRM2 | |
| SCHEMBL13585136 | 0.79 | DNM1 (0.45) | OTCGRIK1GRIK2GRM1GRM2 | |
| SCHEMBL1768892 | 0.78 | GSR (0.48) | OTCGRIK1GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578313-A | Therapeutic use of vitaletheine modulators in neoplasia | THE UNIVERSITY OF NEW MEXICO (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0539525-A4 | — | — | 1994-01-12 | — | — | EP | disclosed |
| EP-0539525-A1 | VITALETHEINE AND USE IN CELL CULTURE AND THERAPY | UNIVERSITY OF NEW MEXICO (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992000955-A1 | VITALETHEINE AND USE IN CELL CULTURE AND THERAPY | UNIVERSITY OF NEW MEXICO (US) | 1992-01-23 | — | — | WO | disclosed |