Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634437 | 1.00 | PTGS1 (0.51) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL29590846 | 0.88 | SLC1A1 (0.58) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL1768542 | 0.83 | GSR (0.52) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL1768540 | 0.83 | GSR (0.52) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL8041596 | 0.83 | GRM8 (0.63) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL1374853 | 0.83 | SLC1A1 (0.52) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL1512875 | 0.83 | SLC1A1 (0.52) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL8041593 | 0.83 | GRM8 (0.63) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL18656205 | 0.82 | OTC (0.59) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL25357016 | 0.81 | ALOX15 (0.64) | PTGS1GSTK1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357750-B2 | Cysteamine prodrugs | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2022-06-14 | — | — | US | disclosed |
| EP-0280741-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5103018-A | Antitumor agent; side effect reduction | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0280741-A1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357750-B2 | Cysteamine prodrugs | SLC7A11, CTH, CBS | PTGS1 684/4885GSTK1 479/4885GRM8 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.