Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761307 | 0.88 | NQO2 (0.48) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL7527351 | 0.83 | TDP1 (0.56) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL4566447 | 0.81 | NR1H2 (0.44) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL23589560 | 0.80 | NQO2 (0.52) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL31558290 | 0.80 | NQO2 (0.52) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL23612586 | 0.78 | ACHE (0.75) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL4180819 | 0.77 | NQO2 (0.43) | NQO2ACHEALDH1A1RAB9AGAA | |
| SCHEMBL874110 | 0.76 | TDP1 (0.67) | NQO2ALDH1A1RAB9AGAAMAPT | |
| SCHEMBL4181275 | 0.76 | NR1H2 (0.43) | NQO2MAPTTDP1ADORA3ADORA1 | |
| SCHEMBL11808972 | 0.75 | ADORA3 (0.41) | NQO2ACHEALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529999-A | SULFONAMIDOQUINOXALINE DERIVATIVE | ELI LILLY AND COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0672662-A1 | Quinoxaline derivative used in the treatment of tumours | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |