Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081915 | 0.84 | — | — | |
| SCHEMBL4786657 | 0.84 | — | — | |
| Alcohol SCHEMBL3098774 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL16071907 | 0.77 | — | — | |
| SCHEMBL24348116 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL181414 | 0.73 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26205 | 0.73 | — | — | |
| SCHEMBL28611724 | 0.73 | — | — | |
| SCHEMBL13362255 | 0.73 | — | — | |
| SCHEMBL3664329 | 0.73 | PRMT3 (0.31) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541189-A | Substituted aliphatic amine-containing macrocyclic immunomodulators | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| US-5457194-A | Immunosuppressants | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | disclosed |
| WO-1994021253-A1 | SUBSTITUTED ALIPHATIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |