⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306782 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL2532395 | 0.74 | — | — | |
| SCHEMBL23467005 | 0.73 | — | — | |
| SCHEMBL5801802 | 0.73 | — | — | |
| SCHEMBL28069866 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL6665942 | 0.69 | FDPS (0.33) | — | |
| SCHEMBL10937538 | 0.67 | TSHR (0.38) | — | |
| SCHEMBL8648090 | 0.67 | — | — | |
| SCHEMBL7522629 | 0.67 | LMNA (0.40) | — | |
| SCHEMBL1244563 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554634-A | HYPOTENSIVE | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-10 | — | — | US | disclosed |
| CN-1090278-A | Blood vessel tension peptide protoenzyme inhibitor-N-(2-amino-2-oxygen ethyl) succinic diamide derivative | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-08-03 | — | — | CN | disclosed |
| CN-1087625-A | N-(hydroxyethyl) succinic diamide derivative | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-06-08 | — | — | CN | disclosed |