Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077704 | 0.81 | MEN1 (0.57) | ALDH1A1MEN1KMT2AGRIN2BKDM2B | |
| SCHEMBL9076966 | 0.81 | KDM2B (0.59) | ALDH1A1MEN1KMT2AGRIN2BKDM2B | |
| SCHEMBL9076918 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2AGRIN2BKDM2B | |
| SCHEMBL9078483 | 0.78 | KDM2B (0.59) | ALDH1A1MEN1KMT2AGRIN2BKDM2B | |
| Hydrochloric Acid SCHEMBL9077304 | 0.78 | KDM2B (0.58) | ALDH1A1MEN1KMT2AGRIN2BKDM2B | |
| SCHEMBL9625464 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGRIN2BTSHR | |
| SCHEMBL10646175 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGRIN2BTSHR | |
| Hydrochloric Acid SCHEMBL9624458 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AGRIN2BTSHR | |
| Hydrochloric Acid SCHEMBL9624778 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AGRIN2BTSHR | |
| SCHEMBL9444257 | 0.74 | KCNH2 (0.60) | ALDH1A1MEN1KMT2AGRIN2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532629-B1 | 1-PIPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES | MERRELL PHARMA INC (US) | 1996-11-06 | — | — | EP | disclosed |
| US-5478846-A | 1-piperidinyl alkanoylanyl sulfonamides for treatment of cardiac arrhythmia | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0532629-A4 | — | — | 1994-03-09 | — | — | EP | disclosed |
| EP-0532629-A1 | 1-PYPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018603-A1 | 1-PYPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |