Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077465 | 0.86 | CYP2D6 (0.45) | GRIN2BALDH1A1MAPTKCNH2MEN1 | |
| SCHEMBL9077025 | 0.84 | KCNH2 (0.50) | GRIN2BALDH1A1MAPTKCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL9078685 | 0.83 | KCNH2 (0.51) | GRIN2BALDH1A1MAPTKCNH2MEN1 | |
| SCHEMBL9079349 | 0.79 | CYP2D6 (0.58) | GRIN2BALDH1A1MAPTKCNH2HTR2A | |
| SCHEMBL9077057 | 0.77 | CYP2D6 (0.53) | MAPTKCNH2MEN1KMT2AHTR2A | |
| SCHEMBL9076918 | 0.77 | MEN1 (0.47) | GRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL9444257 | 0.74 | KCNH2 (0.60) | GRIN2BALDH1A1MAPTKCNH2MEN1 | |
| SCHEMBL9077056 | 0.74 | KCNH2 (0.53) | ALDH1A1MAPTKCNH2MEN1KMT2A | |
| SCHEMBL8958724 | 0.74 | SMN1; SMN2 (0.63) | ALDH1A1KCNH2MEN1KMT2AHTR2A | |
| SCHEMBL10646175 | 0.73 | ALDH1A1 (0.56) | GRIN2BALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532629-B1 | 1-PIPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES | MERRELL PHARMA INC (US) | 1996-11-06 | — | — | EP | claimed |