Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TYMS | P04818 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041820 | 0.79 | ALDH1A1 (0.63) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL9078978 | 0.79 | TYMS (0.46) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL9080061 | 0.79 | TYMS (0.46) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL9077954 | 0.75 | TYMS (0.43) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL9077614 | 0.75 | ALDH1A1 (0.54) | TYMSALDH1A1TSHRHIF1AHSD17B10 | |
| SCHEMBL9039794 | 0.75 | TYMS (0.46) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL3851765 | 0.75 | TYMS (0.58) | CA1CA2TYMS | |
| SCHEMBL9078243 | 0.72 | TYMS (0.45) | TYMSALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL26750980 | 0.72 | CA1 (0.51) | CA1CA2ALDH1A1HPGDTSHR | |
| SCHEMBL9079018 | 0.71 | KMT2A (0.49) | TYMSALDH1A1HPGDCASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585382-A | ANTICARCINOGENIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5416089-A | Antitumor agent | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |