Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391282 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4ERECQLKMT2A | |
| SCHEMBL28973299 | 0.81 | IAPP (0.43) | ALDH1A1HSD17B10MEN1KMT2ABCL9 | |
| SCHEMBL28397444 | 0.80 | BCL9 (0.38) | ALDH1A1HSD17B10KDM4EMEN1RECQL | |
| Hydrochloric Acid SCHEMBL28808106 | 0.79 | BCL9 (0.37) | ALDH1A1HSD17B10KDM4EMEN1RECQL | |
| Hydrochloric Acid SCHEMBL28559470 | 0.79 | BCL9 (0.37) | ALDH1A1HSD17B10KDM4EKMT2ABCL9 | |
| Hydrochloric Acid SCHEMBL28401106 | 0.79 | ABCB11 (0.40) | ALDH1A1HSD17B10KDM4EKMT2ABCL9 | |
| SCHEMBL28820781 | 0.78 | MAPK1 (0.50) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28580531 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL28624434 | 0.75 | BCL9 (0.50) | ALDH1A1KDM4EKMT2ABCL9CTNNB1 | |
| SCHEMBL7106629 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |