SCHEMBL9079646

SCHEMBL9079646

O=C(O)C(I)C(I)(I)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
KIF11 P52732 5/20 0.39
CYP2D6 P10635 2/20 0.38
SRC P12931 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
KCNN4 O15554 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5860569 0.75 MAPT (0.44) CYP1A2KIF11CYP2D6MAPTKMT2A
SCHEMBL5861655 0.71 KIF11 (0.43) CYP1A2KIF11CYP2D6MAPTKMT2A
SCHEMBL2237175 0.70 KCNN4 (0.42) CYP1A2KIF11CYP2D6LMNAMAPK1
SCHEMBL8501130 0.70 CYP1A2 (0.45) CYP1A2KIF11CYP2D6MAPTKMT2A
SCHEMBL9286120 0.68 CYP1A2 (0.45) CYP1A2KIF11CYP2D6SRCMAPT
SCHEMBL1566938 0.67 CYP1A2 (0.52) CYP1A2CYP2D6MAPTKMT2AKCNN4
SCHEMBL7288198 0.67 CYP1A2 (0.48) CYP1A2KIF11CYP2D6SRCMAPT
SCHEMBL4639976 0.67 CYP1A2 (0.48) CYP1A2KIF11CYP2D6SRCMAPT
SCHEMBL6363313 0.67 HDAC3 (0.50) CYP1A2KIF11CYP2D6SRCMAPT
SCHEMBL28959413 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5550263-A PHOSPHOLIPID TO WHICH X-RAY CONTRAST AGENT HAS BEEN COVALENTLY LINKED BY ESTER OR AMIDE BOND KARLSHAMNS LIPIDTEKNIK AB (SE) 1996-08-27 US claimed