Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606118 | 0.80 | KIF11 (0.44) | KIF11CYP2C19HIF1ALMNAHTT | |
| SCHEMBL5861491 | 0.79 | KIF11 (0.43) | KIF11CYP2C19HIF1ALMNAHTT | |
| SCHEMBL5860569 | 0.76 | MAPT (0.44) | KIF11CYP2C19HIF1ACYP1A2CYP2D6 | |
| SCHEMBL12238644 | 0.75 | CYP2C19 (0.44) | KIF11CYP2C19HIF1ACYP1A2CYP2D6 | |
| SCHEMBL27976218 | 0.75 | CYP2C19 (0.44) | CYP2C19HIF1ALMNACYP1A2CYP2D6 | |
| SCHEMBL4638235 | 0.73 | KIF11 (0.39) | KIF11CYP2C19HIF1ACYP1A2CYP2D6 | |
| SCHEMBL11372241 | 0.72 | MAPT (0.40) | KIF11CYP2C19HIF1ALMNAHTT | |
| SCHEMBL7914381 | 0.72 | CYP2C19 (0.46) | KIF11CYP2C19LMNACYP1A2CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL27615501 | 0.72 | LMNA (0.42) | KIF11CYP2C19LMNACYP1A2CYP2D6 | |
| SCHEMBL9079646 | 0.71 | CYP1A2 (0.40) | KIF11CYP2C19HIF1ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |