Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772424 | 0.82 | LMNA (0.49) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL13228906 | 0.75 | NPSR1 (0.44) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL7668283 | 0.74 | NPSR1 (0.43) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL9423133 | 0.72 | TSHR (0.47) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL8632437 | 0.72 | LMNA (0.44) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL7698795 | 0.69 | NPSR1 (0.44) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL10232133 | 0.67 | LMNA (0.43) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL18210830 | 0.67 | HSD17B10 (0.58) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL8632439 | 0.66 | NPSR1 (0.65) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL8686610 | 0.65 | NPSR1 (0.38) | LMNANPSR1MEN1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543514-A | Water-soluble sapphyrins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-08-06 | — | — | US | disclosed |