Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986727 | 0.78 | CA1 (0.57) | HTTSMN1; SMN2SIGMAR1PPARG | |
| SCHEMBL6160452 | 0.77 | ATM (0.58) | ALDH1A1PPARGPPARAEPHX2KCNT1 | |
| SCHEMBL6160451 | 0.77 | ATM (0.58) | ALDH1A1PPARGPPARAEPHX2KCNT1 | |
| SCHEMBL14438287 | 0.77 | LTA4H (0.50) | KDM4EALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL11792666 | 0.75 | SIGMAR1 (0.48) | KDM4ESIGMAR1CASR | |
| SCHEMBL8691568 | 0.73 | SIGMAR1 (0.51) | KDM4EALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL8826024 | 0.73 | SIGMAR1 (0.51) | KDM4EALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL8692762 | 0.73 | SIGMAR1 (0.51) | KDM4EALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL8499037 | 0.73 | SMN1; SMN2 (0.66) | KDM4EALDH1A1HTTSMN1; SMN2CASR | |
| SCHEMBL8694072 | 0.73 | SMN1; SMN2 (0.66) | KDM4EALDH1A1HTTSMN1; SMN2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |