Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | AHCY | P23526 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RBBP5 | Q15291 | 2/20 | 0.46 |
| ▸ | DPY30 | Q9C005 | 2/20 | 0.46 |
| ▸ | ASH2L | Q9UBL3 | 2/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813641 | 0.86 | AHCY (0.55) | DOT1LAHCYKMT2AADAPOLB | |
| SCHEMBL19813690 | 0.86 | AHCY (0.55) | DOT1LAHCYKMT2AADAPOLB | |
| SCHEMBL19813648 | 0.86 | AHCY (0.55) | DOT1LAHCYKMT2AADAPOLB | |
| SCHEMBL9079438 | 0.86 | LARS1 (0.51) | DOT1LAHCYKMT2AADAPOLB | |
| SCHEMBL7882267 | 0.84 | P2RX3 (0.54) | DOT1LKMT2AADAPOLB | |
| SCHEMBL7882271 | 0.84 | P2RX3 (0.54) | DOT1LKMT2AADAPOLB | |
| SCHEMBL9193969 | 0.84 | P2RX3 (0.54) | DOT1LKMT2AADAPOLB | |
| SCHEMBL9193964 | 0.84 | P2RX3 (0.54) | DOT1LKMT2AADAPOLB | |
| SCHEMBL24787577 | 0.84 | ADA (0.48) | DOT1LAHCYKMT2AADAPOLB | |
| SCHEMBL23105026 | 0.84 | ADA (0.48) | DOT1LAHCYKMT2AADAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355131-B1 | ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF | PRO NEURON INC (US) | 1996-09-04 | — | — | EP | disclosed |