Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.51 |
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081733 | 0.84 | PPARG (0.47) | PPARGPPARAFFAR1SRD5A2PPARD | |
| SCHEMBL9080851 | 0.81 | POLB (0.53) | PPARGPPARAPOLBFFAR1SRD5A2 | |
| SCHEMBL9081185 | 0.80 | PPARG (0.46) | PPARGPPARAPOLBFFAR1SRD5A2 | |
| SCHEMBL9079799 | 0.80 | POLB (0.51) | POLBFFAR1SRD5A2LTA4H | |
| SCHEMBL9081612 | 0.80 | PPARG (0.51) | PPARGPPARAPOLBFFAR1SRD5A2 | |
| SCHEMBL9081807 | 0.78 | NPY5R (0.48) | FFAR1NPY5R | |
| SCHEMBL522949 | 0.78 | POLB (0.77) | POLBSRD5A2ALDH1A1 | |
| SCHEMBL30287662 | 0.78 | POLB (0.77) | POLBSRD5A2ALDH1A1 | |
| SCHEMBL28576596 | 0.76 | POLB (0.75) | POLBFFAR1SRD5A2ALDH1A1 | |
| SCHEMBL27703521 | 0.76 | MTNR1A (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |