Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081184 | 0.84 | NR3C1 (0.49) | POLBNR3C1PTGESSRD5A2STAT3 | |
| SCHEMBL9080554 | 0.82 | LPAR1 (0.49) | POLBNR3C1PTGESSRD5A2STAT3 | |
| SCHEMBL9081408 | 0.81 | POLB (0.50) | POLBNR3C1PTGESSTAT3LPAR1 | |
| SCHEMBL9080906 | 0.81 | LPAR1 (0.58) | POLBPTGESSTAT3LPAR1LPAR5 | |
| SCHEMBL9080531 | 0.80 | TSHR (0.55) | NR3C1STAT3LPAR1LPAR5TSHR | |
| SCHEMBL9080371 | 0.80 | TSHR (0.55) | NR3C1STAT3LPAR1LPAR5TSHR | |
| SCHEMBL9081179 | 0.80 | PTGES (0.59) | NR3C1PTGESSRD5A2LPAR1LPAR5 | |
| SCHEMBL9081721 | 0.80 | TSHR (0.55) | NR3C1STAT3LPAR1LPAR5TSHR | |
| SCHEMBL9081215 | 0.80 | TSHR (0.55) | NR3C1STAT3LPAR1LPAR5TSHR | |
| SCHEMBL9079983 | 0.80 | PPARG (0.51) | POLBSRD5A2FFAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |