Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 6/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079990 | 0.89 | TP53 (0.41) | LMNAKMT2ASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL9233356 | 0.88 | HDAC1 (0.43) | LMNAMAPK1PTGESMEN1KMT2A | |
| SCHEMBL9082579 | 0.86 | TYK2 (0.37) | TYK2PTGESJAK2JAK1MEN1 | |
| Hydrochloric Acid SCHEMBL9080397 | 0.83 | HDAC1 (0.39) | TYK2LMNAPTGESJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL9080756 | 0.81 | TYK2 (0.44) | TYK2LMNAPTGESJAK2JAK1 | |
| SCHEMBL9081142 | 0.80 | POLB (0.47) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL9082584 | 0.78 | PTGES (0.38) | TYK2PTGESJAK2JAK1MEN1 | |
| SCHEMBL9080031 | 0.78 | KMT2A (0.45) | TYK2PTGESJAK2JAK1MEN1 | |
| SCHEMBL9081108 | 0.78 | KMT2A (0.45) | TYK2PTGESJAK2JAK1MEN1 | |
| SCHEMBL9080202 | 0.77 | TYK2 (0.38) | TYK2LMNAMAPK1PTGESJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |