Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079987 | 0.89 | TYK2 (0.36) | SMN1; SMN2KMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL9233356 | 0.88 | HDAC1 (0.43) | TP53SMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL9082584 | 0.86 | PTGES (0.38) | SMN1; SMN2KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL9080397 | 0.83 | HDAC1 (0.39) | SMN1; SMN2POLBKMT2ALMNARAB9A | |
| Hydrochloric Acid SCHEMBL9080756 | 0.81 | TYK2 (0.44) | SMN1; SMN2POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL9081142 | 0.80 | POLB (0.47) | TP53SMN1; SMN2POLBKMT2ARAB9A | |
| SCHEMBL9082579 | 0.78 | TYK2 (0.37) | SMN1; SMN2POLBKMT2A | |
| SCHEMBL9080031 | 0.78 | KMT2A (0.45) | SMN1; SMN2POLBKMT2AHPGD | |
| SCHEMBL9081108 | 0.78 | KMT2A (0.45) | SMN1; SMN2POLBKMT2AHPGD | |
| SCHEMBL9080202 | 0.77 | TYK2 (0.38) | SMN1; SMN2POLBKMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |