Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811901 | 1.00 | DHODH (0.62) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL5914887 | 0.93 | DHODH (0.70) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL5914889 | 0.93 | DHODH (0.70) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL8810121 | 0.89 | DHODH (0.74) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL9080958 | 0.89 | DHODH (0.74) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL8812418 | 0.87 | DHODH (0.63) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL9081360 | 0.87 | DHODH (0.63) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL9080385 | 0.86 | DHODH (0.62) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL8810683 | 0.86 | DHODH (0.62) | DHODHMEN1KMT2AG6PDCACNA1B | |
| SCHEMBL8811754 | 0.86 | DHODH (0.63) | DHODHMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532259-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5494911-A | TREATING LEUKEMIA, SARCOMA, CARCINOMA, LYMPHOMA, SKIN CANCER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-27 | — | — | US | disclosed |