Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810121 | 1.00 | DHODH (0.74) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL8812418 | 0.90 | DHODH (0.63) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9081360 | 0.90 | DHODH (0.63) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9080225 | 0.89 | DHODH (0.62) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL8810683 | 0.89 | DHODH (0.62) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL8811754 | 0.89 | DHODH (0.63) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL8811901 | 0.89 | DHODH (0.62) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL8809976 | 0.89 | DHODH (0.63) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9080385 | 0.89 | DHODH (0.62) | DHODHALDH1A1L3MBTL1RAB9AMEN1 | |
| SCHEMBL3250476 | 0.88 | DHODH (0.82) | DHODHALDH1A1L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532259-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5494911-A | TREATING LEUKEMIA, SARCOMA, CARCINOMA, LYMPHOMA, SKIN CANCER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-27 | — | — | US | disclosed |