Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 8/20 | 0.60 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.47 |
| ▸ | HNMT | P50135 | 2/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.47 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | INMT | O95050 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.47 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079438 | 0.88 | LARS1 (0.51) | MARS1DOT1LEHMT2KMT2AADA | |
| SCHEMBL24787577 | 0.85 | ADA (0.48) | DOT1LKMT2AADA | |
| SCHEMBL23105026 | 0.85 | ADA (0.48) | DOT1LKMT2AADA | |
| SCHEMBL9079835 | 0.83 | DOT1L (0.48) | DOT1LDNMT1CARM1DNMT3BNNMT | |
| SCHEMBL9466654 | 0.83 | ADA (0.53) | DOT1LKMT2AADA | |
| SCHEMBL9466645 | 0.83 | ADA (0.53) | DOT1LKMT2AADA | |
| SCHEMBL16715233 | 0.82 | MARS1 (0.72) | MARS1DOT1LDNMT1CARM1EHMT2 | |
| SCHEMBL16715232 | 0.82 | MARS1 (0.72) | MARS1DOT1LDNMT1CARM1EHMT2 | |
| SCHEMBL16715229 | 0.82 | MARS1 (0.72) | MARS1DOT1LDNMT1CARM1EHMT2 | |
| SCHEMBL16715231 | 0.82 | MARS1 (0.72) | MARS1DOT1LDNMT1CARM1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355131-B1 | ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF | PRO NEURON INC (US) | 1996-09-04 | — | — | EP | disclosed |