Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | RGS4 | P49798 | 1/20 | 0.44 |
| ▸ | RGS8 | P57771 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530478 | 0.79 | APOBEC3G (0.61) | CFTRKDM4EALDH1A1GRIA1GRIA2 | |
| SCHEMBL7329647 | 0.79 | APOBEC3G (0.61) | CFTRKDM4EALDH1A1GRIA1GRIA2 | |
| SCHEMBL24335163 | 0.77 | ALDH1A1 (0.48) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL29580281 | 0.77 | ALDH1A1 (0.48) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL29482656 | 0.77 | KMT2A (0.48) | KDM4EALDH1A1BRD4HPGDTSHR | |
| SCHEMBL28702303 | 0.77 | KMT2A (0.48) | KDM4EALDH1A1BRD4HPGDTSHR | |
| SCHEMBL10508287 | 0.75 | PARG (0.53) | HDAC1HDAC8HDAC6PGRKDM4E | |
| SCHEMBL9080167 | 0.74 | CA12 (0.52) | HDAC1HDAC8HDAC6PGRKDM4E | |
| SCHEMBL28691251 | 0.73 | CFTR (0.52) | CFTRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30581508 | 0.73 | CFTR (0.52) | CFTRKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559106-A | Heterocyclic compounds, their use and preparation | NOVO NORDISK A/S (DK) | 1996-09-24 | — | — | US | disclosed |
| EP-0691969-A1 | [1,2,4] TRIAZOLO [4,3-a] QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994021639-A1 | [1,2,4] TRIAZOLO [4,3-a] QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-09-29 | — | — | WO | disclosed |