Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080239 | 0.93 | ALOX5 (0.51) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080166 | 0.93 | ALOX5 (0.51) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080837 | 0.90 | ALOX5 (0.52) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080659 | 0.89 | ALOX5 (0.53) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080789 | 0.85 | ALOX5 (0.49) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9081529 | 0.83 | ALOX5 (0.58) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080782 | 0.83 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9326000 | 0.80 | ALOX5 (0.59) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9136256 | 0.80 | ALOX5 (0.57) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9325979 | 0.80 | ALOX5 (0.58) | ALOX5CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519022-A | α, α dialkylbenzyl derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-05-21 | — | — | US | claimed |
| US-5288742-A | Lipoxygenase inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-22 | — | — | US | claimed |
| EP-0505122-A1 | Alpha, alpha-dialkylbenzyl derivatives | ZENECA LIMITED (GB) | 1992-09-23 | — | — | EP | claimed |
| US-5519022-A | α, α dialkylbenzyl derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-05-21 | — | — | US | disclosed |
| US-5288742-A | Lipoxygenase inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-22 | — | — | US | disclosed |
| EP-0505122-A1 | Alpha, alpha-dialkylbenzyl derivatives | ZENECA LIMITED (GB) | 1992-09-23 | — | — | EP | disclosed |