Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326000 | 0.91 | ALOX5 (0.59) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9325922 | 0.87 | ALOX5 (0.54) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9081529 | 0.84 | ALOX5 (0.58) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080659 | 0.81 | ALOX5 (0.53) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080279 | 0.80 | ALOX5 (0.55) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9326493 | 0.77 | ALOX5 (0.52) | ALOX5MAOB | |
| SCHEMBL9080239 | 0.76 | ALOX5 (0.51) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080789 | 0.75 | ALOX5 (0.49) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080166 | 0.75 | ALOX5 (0.51) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9080837 | 0.74 | ALOX5 (0.52) | ALOX5CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298511-A | Alkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-29 | — | — | US | claimed |
| EP-0540165-A1 | Alkanoic acid derivatives | ZENECA LIMITED (GB) | 1993-05-05 | — | — | EP | claimed |
| US-5298511-A | Alkanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-29 | — | — | US | disclosed |
| EP-0540165-A1 | Alkanoic acid derivatives | ZENECA LIMITED (GB) | 1993-05-05 | — | — | EP | disclosed |