Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | PKM | P14618 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562612 | 0.83 | RAB9A (0.66) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL1147615 | 0.81 | NPC1 (0.63) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL1185009 | 0.81 | NPC1 (0.63) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL9586710 | 0.80 | NPC1 (0.56) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL9586718 | 0.80 | NPC1 (0.56) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL17667006 | 0.79 | DHODH (0.60) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL17667009 | 0.79 | DHODH (0.60) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL14404856 | 0.79 | DHODH (0.60) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL8554529 | 0.79 | RAB9A (0.59) | NPC1RAB9APKMGAALMNA | |
| SCHEMBL438214 | 0.79 | RAB9A (0.70) | NPC1RAB9APKMGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |