Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668737 | 0.82 | TSHR (0.46) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL19668416 | 0.82 | TSHR (0.54) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL21588945 | 0.81 | ALDH1A1 (0.47) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL28996726 | 0.80 | TSHR (0.42) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL10992413 | 0.78 | TSHR (0.43) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL424554 | 0.77 | CYP2D6 (0.46) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL3366935 | 0.75 | TSHR (0.51) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL28966865 | 0.74 | KDM4E (0.39) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL10591727 | 0.74 | LMNA (0.40) | TSHRPOLBKMT2AHTTNPC1 | |
| SCHEMBL660286 | 0.74 | MAPT (0.54) | TSHRKMT2ANPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |