Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL6360803 | 0.95 | MEN1 (0.67) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10054993 | 0.89 | MEN1 (0.74) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL9320030 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16812954 | 0.88 | SMN1; SMN2 (0.75) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15417039 | 0.87 | LMNA (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL17447224 | 0.87 | HTT (0.57) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| Benzene SCHEMBL11697595 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL5799878 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL1654 | 0.87 | MEN1 (0.78) | MEN1KMT2ATDP1BCHEMAOA | |
| SCHEMBL10133040 | 0.85 | GAA (0.77) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |