Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403960 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7327928 | 0.89 | HRH3 (0.59) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7405428 | 0.89 | HRH3 (0.46) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7404981 | 0.85 | HRH3 (0.44) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7407224 | 0.84 | ALDH1A1 (0.53) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7399584 | 0.83 | GAA (0.47) | ITGB3ITGA2BHRH3HRH1MEN1 | |
| SCHEMBL7442786 | 0.83 | HRH3 (0.43) | ITGB3ITGA2BHRH3POLBMEN1 | |
| SCHEMBL7402638 | 0.82 | ALDH1A1 (0.51) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7403828 | 0.81 | MEN1 (0.49) | ITGB3ITGA2BHRH3POLBHRH1 | |
| SCHEMBL7398926 | 0.81 | ALDH1A1 (0.62) | HRH3POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |