SCHEMBL9080667

SCHEMBL9080667

CCC[Si](Cl)(Cl)C[Si](Cl)(Cl)CCCCl

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8053599 0.90 TSHR (0.45) TSHRTDP1ALDH1A1
SCHEMBL9079826 0.87 TSHR (0.38) TSHRTDP1ALDH1A1
SCHEMBL707091 0.84
SCHEMBL707286 0.78 TSHR (0.35) TSHRTDP1ALDH1A1
SCHEMBL8960739 0.76
SCHEMBL9122036 0.76 ALDH1A1 (0.33) TSHRTDP1ALDH1A1
SCHEMBL705897 0.75 TSHR (0.30) TSHRTDP1
SCHEMBL704861 0.75 TSHR (0.30) TSHRTDP1
SCHEMBL8050672 0.75 TSHR (0.57) TSHRTDP1ALDH1A1
SCHEMBL8053707 0.74 TSHR (0.43) TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527934-A HYDROSILATING BIS(DICHLOROSILYL)METHANES WITH ORGANOOLEFINS OR ORGANOSILYLOLEFINS IN THE PRESENCE OF CHLOROPLATINIC ACID CATALYST KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1996-06-18 US disclosed