Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 2/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921995 | 0.98 | MEN1 (0.50) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL2839828 | 0.92 | MEN1 (0.52) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL4936947 | 0.82 | MEN1 (0.38) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL16240018 | 0.79 | FAAH (0.43) | MEN1KMT2ACYP3A4MAPTTHRB | |
| SCHEMBL4751225 | 0.78 | MEN1 (0.50) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL691872 | 0.78 | MEN1 (0.46) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL691873 | 0.78 | MEN1 (0.46) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL10897479 | 0.75 | ABCG2 (0.49) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL10897482 | 0.75 | ABCG2 (0.49) | MEN1KMT2ACYP3A4PTGS1PPARG | |
| SCHEMBL7648924 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP3A4PTGS1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482970-A | CONTROLLING MEMBRANE PERMEATION AND METABOLISM | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-01-09 | — | — | US | disclosed |