SCHEMBL4751225

SCHEMBL4751225

[CH2]C(C=CCCC)C=CCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CYP3A4 P08684 1/20 0.50
PTGS1 P23219 1/20 0.43
PPARG P37231 1/20 0.43
OPRK1 P41145 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
SPHK2 Q9NRA0 4/20 0.43
SPHK1 Q9NYA1 4/20 0.43
MAPT P10636 3/20 0.43
CETP P11597 3/20 0.43
GMNN O75496 2/20 0.43
LMNA P02545 2/20 0.43
GLA P06280 2/20 0.43
POLB P06746 2/20 0.43
THRB P10828 2/20 0.43
MAPK1 P28482 2/20 0.43
CXCR5 P32302 2/20 0.43
CCR6 P51684 2/20 0.43
BLM P54132 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28709594 0.93 MEN1 (0.57) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL60120 0.91 MEN1 (0.55) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL852481 0.82 MEN1 (0.41) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL22653991 0.82 MEN1 (0.41) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL5209281 0.81 TSHR (0.33) MEN1KMT2ACYP3A4TSHR
SCHEMBL2121174 0.79 MEN1 (0.52) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL2171745 0.79 TSHR (0.32) MEN1KMT2ACYP3A4TSHR
SCHEMBL2121177 0.79 MEN1 (0.52) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL9080744 0.78 MEN1 (0.47) MEN1KMT2ACYP3A4PTGS1PPARG
SCHEMBL28237365 0.77 MEN1 (0.55) MEN1KMT2ACYP3A4PTGS1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931445-B2 Composition comprising baicalin L'OREAL (FR) 2024-03-19 US disclosed
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-01-18 US disclosed
EP-3558253-B1 COMPOSITION COMPRISING BAICALIN OREAL (FR) 2022-12-28 EP disclosed
US-20200093724-A1 COMPOSITION COMPRISING BAICALIN L'OREAL (FR) 2020-03-26 US disclosed
EP-3558253-A1 COMPOSITION COMPRISING BAICALIN L'Oreal (FR) 2019-10-30 EP disclosed
EP-3525788-A1 TREATMENT OF SYNUCLEINOPATHIES Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) (DE) 2019-08-21 EP disclosed
EP-3493790-A1 METHODS FOR THE PREPARATION OF LIPOSOMES Curirx Inc. (US) 2019-06-12 EP disclosed
CN-109846884-A With TOR kinase inhibitor for treating cancer 西格诺药品有限公司 2019-06-07 CN disclosed
WO-2018115493-A1 COMPOSITION COMPRISING BAICALIN L'OREAL (FR) 2018-06-28 WO disclosed
WO-2018115360-A1 COMPOSITION COMPRISING BAICALIN, A FATTY ACID ESTER AND AN ALKYLPOLYGLYCOSIDE L'OREAL (FR) 2018-06-28 WO disclosed
WO-2012158844-A1 HETEROCYCLIC COMPOUNDS SHIONOGI & CO., LTD. (JP) 2012-11-22 WO disclosed
WO-2012085648-A1 PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF PURDUE PHARMA L.P. (US) 2012-06-28 WO disclosed
WO-2008133801-A1 CERAMIDE DERIVATIVES AS MODULATORS OF IMMUNITY AND AUTOIMMUNITY ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2008-11-06 WO disclosed
EP-1974013-A2 IMPROVED COMPOSITION FOR COLLECTING AND PRESERVING PLACENTAL STEM CELLS AND METHODS OF USING THE COMPOSITION Anthrogenesis Corporation (US) 2008-10-01 EP disclosed
WO-2007079185-A2 IMPROVED COMPOSITION FOR COLLECTING AND PRESERVING PLACENTAL STEM CELLS AND METHODS OF USING THE COMPOSITION ANTHROGENESIS CORPORATION (US) 2007-07-12 WO disclosed
WO-2005056524-A2 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 2005-06-23 WO disclosed
EP-1542991-A1 PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS Euro-Celtique, S.A. (LU) 2005-06-22 EP disclosed
EP-1507528-A2 METHODS FOR USING JNK INHIBITORS FOR TREATING OR PREVENTING DISEASE-RELATED WASTING Signal Pharmaceuticals, Inc. (US) 2005-02-23 EP disclosed
WO-2004029044-A1 PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS EURO-CELTIQUE, S.A. (LU) 2004-04-08 WO disclosed
WO-2003099221-A2 METHODS FOR USING JNK INHIBITORS FOR TREATING OR PREVENTING DISEASE-RELATED WASTING SIGNAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11931445-B2 Composition comprising baicalin KRT18, S100A6, DSG1 MEN1 1651/4885KMT2A 4129/4885CYP3A4 2421/4885
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG MEN1 2375/4885KMT2A 2744/4885CYP3A4 3564/4885
US-20200093724-A1 COMPOSITION COMPRISING BAICALIN KRT18, S100A6, DSG1 MEN1 1651/4885KMT2A 4129/4885CYP3A4 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.