Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080745 | 0.80 | GSTO1 (0.40) | BACE1KDM4ENPC1LMNARAB9A | |
| SCHEMBL20199872 | 0.72 | DRD4 (0.42) | KDM4ELMNASMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL14905959 | 0.70 | GSK3A (0.40) | KDM4EGAALMNAL3MBTL1CHRM2 | |
| SCHEMBL21401295 | 0.70 | GSK3A (0.40) | KDM4EGAALMNAL3MBTL1CHRM2 | |
| SCHEMBL27383795 | 0.70 | GSK3A (0.40) | KDM4EGAALMNAL3MBTL1CHRM2 | |
| Tromethamine SCHEMBL9264448 | 0.69 | GSTO1 (0.38) | KDM4ENPC1LMNARAB9AUSP30 | |
| SCHEMBL25422192 | 0.69 | ALDH1A1 (0.49) | NPC1LMNARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2811174 | 0.69 | ALDH1A1 (0.49) | NPC1LMNARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL28519312 | 0.69 | ALDH1A1 (0.49) | NPC1LMNARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL12004770 | 0.69 | ALDH1A1 (0.49) | NPC1LMNARAB9AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |