Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.47 |
| ▸ | ATP4B | P51164 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081462 | 0.87 | KMT2A (0.48) | ATP4AATP4BKMT2AMEN1CYP3A4 | |
| SCHEMBL9081771 | 0.86 | MEN1 (0.42) | ATP4AATP4BKMT2AMEN1CYP3A4 | |
| SCHEMBL9080517 | 0.85 | KMT2A (0.49) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9080622 | 0.85 | KMT2A (0.46) | KMT2AMEN1CYP3A4MAPK1CRHBP | |
| SCHEMBL9081500 | 0.84 | KMT2A (0.46) | KMT2AMEN1CYP3A4CRHBPHTT | |
| SCHEMBL9231591 | 0.84 | PTGES (0.46) | KMT2AMEN1CRHBPHTTCRHR2 | |
| SCHEMBL9081354 | 0.83 | KMT2A (0.48) | KMT2AMEN1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9080404 | 0.83 | KMT2A (0.48) | KMT2AMEN1CYP3A4CRHBPHTT | |
| SCHEMBL9081886 | 0.83 | KMT2A (0.45) | ATP4AATP4BKMT2AMEN1CYP3A4 | |
| SCHEMBL9082430 | 0.83 | KMT2A (0.45) | KMT2AMEN1CRHBPHTTCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |