Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080918 | 0.86 | AHR (0.36) | AHRPDK2ADORA2ANPC1TP53 | |
| SCHEMBL2172208 | 0.79 | ADORA2A (0.43) | PDK2ADORA2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11222467 | 0.74 | KDM4E (0.34) | TSHR | |
| SCHEMBL18606039 | 0.70 | — | — | |
| SCHEMBL2172214 | 0.68 | ADORA2A (0.43) | PDK2ADORA2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29035097 | 0.67 | AHR (0.35) | AHRPDK2NPC1TP53HPGD | |
| Piperazine SCHEMBL14965379 | 0.66 | HTR2C (0.37) | — | |
| SCHEMBL11528492 | 0.65 | CYP2A6 (0.39) | PDK2ADORA2ANPC1TP53HPGD | |
| Naphthoquinone SCHEMBL20378412 | 0.64 | IDO1 (0.50) | TP53HPGDLMNATSHR | |
| SCHEMBL28025414 | 0.64 | CYP2A6 (0.35) | PDK2ADORA2ANPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208673-A | — | — | None | — | — | JP | disclosed |
| JP-H08208673-A | PREPARATION OF 6-ARYL-6H-DIBENZO(C.E)(1,2)OXAPHOSPHORINE | HOECHST AG | 1996-08-13 | — | — | JP | disclosed |