SCHEMBL9080918

SCHEMBL9080918

Clc1cccc2c1-c1ccccc1PO2

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.36
PDK2 Q15119 1/20 0.33
ADORA2A P29274 1/20 0.33
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2A6 P11509 1/20 0.32
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9080913 0.86 AHR (0.36) AHRPDK2ADORA2ANPC1TP53
SCHEMBL2172214 0.79 ADORA2A (0.43) PDK2ADORA2AHPGDRAB9ASMN1; SMN2
SCHEMBL11222467 0.74 KDM4E (0.34) TSHR
SCHEMBL2172208 0.68 ADORA2A (0.43) PDK2ADORA2AHPGDRAB9ASMN1; SMN2
Piperazine SCHEMBL14965379 0.66 HTR2C (0.37)
Naphthoquinone SCHEMBL20378412 0.64 IDO1 (0.50) TP53HPGDLMNATSHR
SCHEMBL259173 0.64 CES1 (0.36) AHRCYP2A6
SCHEMBL2469822 0.64 CYP2A6 (0.55) PDK2ADORA2ANPC1TP53HPGD
SCHEMBL9299768 0.62 TSHR (0.47) PDK2ADORA2ANPC1TP53HPGD
SCHEMBL3267863 0.62 TSHR (0.47) PDK2ADORA2ANPC1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2025-12-23 US claimed
US-20230339994-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 US claimed
WO-2022019021-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE 株式会社伏見製薬所 2022-01-27 WO claimed
JP-8208673-A None JP disclosed
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2025-12-23 US disclosed
US-20230339994-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 US disclosed
EP-4202013-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE Fushimi Pharmaceutical Co., Ltd. (JP) 2023-06-28 EP disclosed
WO-2022019021-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE 株式会社伏見製薬所 2022-01-27 WO disclosed
JP-H08208673-A PREPARATION OF 6-ARYL-6H-DIBENZO(C.E)(1,2)OXAPHOSPHORINE HOECHST AG 1996-08-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339994-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE PFAS, PHOSPHO1, PAF1 AHR 4215/4885PDK2 1970/4885ADORA2A 1679/4885
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure PFAS, PHOSPHO1, PAF1 AHR 4215/4885PDK2 1970/4885ADORA2A 1679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.