Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | FGR | P09769 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172214 | 0.86 | ADORA2A (0.43) | ADORA2APTPRCCSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL9080913 | 0.79 | AHR (0.36) | ADORA2APDK2SMN1; SMN2HPGDRAB9A | |
| SCHEMBL11222467 | 0.74 | KDM4E (0.34) | MAPK1 | |
| SCHEMBL18606039 | 0.70 | — | — | |
| Naphthoquinone SCHEMBL20378412 | 0.64 | IDO1 (0.50) | PTPRCMAOAALDH1A1MEN1POLB | |
| SCHEMBL7389021 | 0.64 | ALDH1A1 (0.67) | ADORA2APTPRCCSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL28547340 | 0.62 | PTPRC (0.67) | ADORA2APTPRCCSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL1578324 | 0.62 | PTPRC (0.67) | ADORA2APTPRCCSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL6760678 | 0.62 | ADORA2A (0.48) | ADORA2APTPRCCSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL11256633 | 0.62 | MAOB (0.47) | ADORA2APTPRCMAOAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973191-B2 | Method for the production of dibenz[c,e] [1,2]-oxaphosphorin derivatives, amino-dibenz[c,e] [1,2]-oxaphosphorin and also use thereof | EMS-PATENT AG (CH) | 2011-07-05 | — | — | US | disclosed |
| US-20100069657-A1 | METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF | EMS-PATENT AG (CH) | 2010-03-18 | — | — | US | disclosed |
| CN-101648976-A | Method for the production of dibenz[c,e] [1,2]-oxaphosphorin derivatives, amino-dibenz[c,e] [1,2]-oxaphosphorin and also use thereof | EMS PATENT AG CH | 2010-02-17 | — | — | CN | disclosed |
| EP-0005441-B1 | AMINODIBENZOXAPHOSPHORINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS STABILISATORS | CIBA-GEIGY AG (CH) | 1982-05-19 | — | — | EP | disclosed |
| EP-0005441-A1 | Aminodibenzoxaphosphorines, process for their preparation and their use as stabilisators | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069657-A1 | METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF | PFAS, PNP, PNPO | ADORA2A 443/4885PTPRC 2350/4885CSNK1A1 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.