Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | CBS | P35520 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081866 | 0.81 | RAB9A (0.48) | CNR1NPC1RAB9AMEN1KMT2A | |
| Iodide SCHEMBL9082499 | 0.80 | CNR1 (0.56) | CNR1NAMPTNPC1RAB9AMEN1 | |
| SCHEMBL4531938 | 0.77 | SMN1; SMN2 (0.46) | CNR1KMT2AALDH1A1 | |
| SCHEMBL9081751 | 0.77 | MAPT (0.64) | CNR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4380054 | 0.75 | NAMPT (0.71) | CNR1NAMPTNPC1RAB9AMEN1 | |
| SCHEMBL11539598 | 0.75 | CNR1 (0.54) | CNR1NAMPTKMT2AALDH1A1CTNNB1 | |
| SCHEMBL9079882 | 0.74 | HTR2B (0.61) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9082883 | 0.74 | MAPT (0.63) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL20557860 | 0.73 | CNR1 (1.00) | CNR1MAPT | |
| SCHEMBL14485379 | 0.73 | CNR1 (0.51) | CNR1NAMPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039382-A1 | UREA DERIVATIVES AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-12 | — | — | WO | disclosed |