Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16507220 | 0.90 | PTPN1 (0.42) | PTPN1HTR7SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29572501 | 0.83 | HTR7 (0.53) | HTR7SMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL755670 | 0.83 | HTR7 (0.53) | HTR7SMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL29493419 | 0.82 | PTPN1 (0.49) | PTPN1SMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL19617278 | 0.82 | PTPN1 (0.49) | PTPN1SMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL6564781 | 0.82 | PTPN1 (0.41) | PTPN1HTR7SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL17919290 | 0.82 | PTPN1 (0.45) | PTPN1HTR7SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6004407 | 0.81 | KCNN4 (0.40) | PTPN1SMN1; SMN2L3MBTL1CYP2C19CHEK1 | |
| SCHEMBL363904 | 0.81 | ALDH1A1 (0.41) | PTPN1SMN1; SMN2MAPTHPGDCYP2C19 | |
| SCHEMBL23074907 | 0.81 | MRGPRX4 (0.46) | PTPN1HTR7SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015111-A1 | METHOD AND INTERMEDIATES FOR THE SYNTHESIS OF KORUPENSAMINES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-05-23 | — | — | WO | disclosed |